Miscarriage Research Today is a free monthly online journal that collates and summarizes the latest research about Miscarriage, including details on signs, symptoms, recurrent, pregnancy. | ||||||
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Miscarriage karyotype and its relationship with maternal body mass index, age, and mode of conception.Kroon B, Harrison K, Martin N, Wong B, Yazdani A Queensland Fertility Group Research Fondation, Brisbane, Queensland, Australia. rkippen@unimelb.edu.au This study investigated the association between miscarriage karyotype and body mass index, maternal age, and mode of conception. Miscarriages after IVF and/or intracytoplasmic sperm injection were less frequently aneuploid; advanced maternal age was associated with an increase in aneuploid products of conception; overweight and obese women aged <35 years were less likely to have aneuploid miscarriages than women in a healthy weight range, suggesting alternate mechanisms for miscarriage in this population. Published 22 March 2011 in Fertil Steril, 95(5): 1827-9. Articles on Miscarriage published 22 March 2011: Increased thrombin generation measured in the presence of thrombomodulin in women with early pregnancy loss. Fertil Steril, 95(5): 1813-5.e1. Compared with 537 parous controls with no history of pregnancy loss, a lower thrombomodulin-related inhibition of the endogenous thrombin potential was measured in 264 cases with previous unexplained pregnancy loss, especially when losses occurred between 9 and 12 weeks of gestation. Adjusting age, protein S, factor VIII, factor V Leiden, and prothrombin G20210A did not change the results. [Abstract] [Full-text] Articles on Miscarriage published 17 March 2011: Progestogen for treating threatened miscarriage. Cochrane Database Syst Rev, 3: CD005943. RIP3 mediates the embryonic lethality of caspase-8-deficient mice. Nature, 471(7338): 368-72. Apoptosis and necroptosis are complementary pathways controlled by common signalling adaptors, kinases and proteases; among these, caspase-8 (Casp8) is critical for death receptor-induced apoptosis. This caspase has also been implicated in non-apoptotic pathways that regulate Fas-associated via death domain (FADD)-dependent signalling and other less defined biological processes as diverse as innate immune signalling and myeloid or lymphoid differentiation patterns. Casp8 suppresses RIP3-RIP1 ... [Abstract] [Full-text] Progestogen for treating threatened miscarriage. Cochrane Database Syst Rev, 3: CD005943. RIP3 mediates the embryonic lethality of caspase-8-deficient mice. Nature, 471(7338): 368-72. Apoptosis and necroptosis are complementary pathways controlled by common signalling adaptors, kinases and proteases; among these, caspase-8 (Casp8) is critical for death receptor-induced apoptosis. This caspase has also been implicated in non-apoptotic pathways that regulate Fas-associated via death domain (FADD)-dependent signalling and other less defined biological processes as diverse as innate immune signalling and myeloid or lymphoid differentiation patterns. Casp8 suppresses RIP3-RIP1 ... [Abstract] [Full-text] Articles on Miscarriage published 15 March 2011: Aberrant expression of imprinted genes in post-implantation rat embryos. Life Sci, 88(13): 634-43. Articles on Miscarriage published 24 January 2011: Hidden mosaicism for a structural chromosome rearrangement: a rare explanation for recurrent miscarriages and affected offspring? Fertil Steril, 95(2): 806-8. We found maternal mosaicism for an unbalanced chromosome rearrangement in a woman with recurrent chromosome rearrangements in the offspring. Hidden mosaicism may be a previously underestimated explanation for recurrent miscarriages and/or affected offspring, and preimplantation genetic diagnosis can be used to verify germinal mosaicism, to evaluate the recurrence risk, and to provide a possibility to achieve a normal pregnancy. [Abstract] [Full-text] Evaluation of a urinary test as a diagnostic tool of a nonprogressive pregnancy. Fertil Steril, 95(2): 783-6. © 2004-2011 Miscarriage Research Today. All Rights Reserved. |
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